Molecular Mechanism of Heart Failure - Publications

Luers C, Hagenah G, Wachter R, Kleta S, Schaumberg J, Riedel S, Binder L, Jung K, Schmidt A, Pieske B: [Importance of surfactant proteins B and D for the differential diagnosis of acute dyspnea]. Med Klin (Munich) 2010;105:611-618.
Luers C, Wachter R, Kleta S, Uhlir M, Koschack J, Scherer M, Binder L, Herrmann-Lingen C, Zapf A, Kulle B, Kochen MM, Pieske B: Natriuretic peptides in the detection of preclinical diastolic or systolic dysfunction. Clin Res Cardiol 2010;99:217-226.
Mehrhof F, Loffler M, Gelbrich G, Özcelik C, Posch M, Hense HW, Keil U, Scheffold T, Schunkert H, Angermann C, Ertl G, Jahns R, Pieske B, Wachter R, Edelmann F, Wollert KC, Maisch B, Pankuweit S, Erbel R, Neumann T, Herzog W, Katus H, Muller-Tasch T, Zugck C, Düngen HD, Regitz-Zagrosek V, Lehmkuhl E, Störk S, Siebert U, Wasem J, Neumann A, Gohler A, Anker SD, Kohler F, Mockel M, Osterziel KJ, Dietz R, Rauchhaus M: A network against failing hearts - introducing the German "Competence Network Heart Failure". Int J Cardiol 2010;145:135-138.
An J, Li P, Li J, Dietz R, Donath S: ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity. J Mol Med 2009;87:401-410.
Schmechel A, Grimm M, El-Armouche A, Hoppner G, Schwoerer AP, Ehmke H, Eschenhagen T: Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects. Cardiovasc Res 2009;82:100-106.
Fraccarollo D, Galuppo P, Schraut S, Kneitz S, van Rooijen N, Ertl G, Bauersachs J: Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response. Hypertension 2008;51:905-914.
Fraccarollo D, Widder JD, Galuppo P, Thum T, Tsikas D, Hoffmann M, Ruetten H, Ertl G, Bauersachs J: Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction. Circulation 2008;118:818-827.
Van Linthout S, Seeland U, Riad A, Eckhardt O, Hohl M, Dhayat N, Richter U, Fischer JW, Bohm M, Pauschinger M, Schultheiss HP, Tschöpe C: Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy. Basic Res Cardiol 2008;103:319-327.
Engelhardt S: Alternative signaling: cardiomyocyte β1-adrenergic receptors signal through EGFRs. J Clin Invest 2007;117:2396-2398.
Seeland U, Selejan S, Engelhardt S, Muller P, Lohse MJ, Bohm M: Interstitial remodeling in beta1-adrenergic receptor transgenic mice. Basic Res Cardiol 2007;102:183-193.
Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J: MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 2007;116:258-267.
Thum T, Hoeber S, Froese S, Klink I, Stichtenoth DO, Galuppo P, Jakob M, Tsikas D, Anker SD, Poole-Wilson PA, Borlak J, Ertl G, Bauersachs J: Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1. Circ Res 2007;100:434-443.
Donath S, Li P, Willenbockel C, Al-Saadi N, Gross V, Willnow T, Bader M, Martin U, Bauersachs J, Wollert KC, Dietz R, von Harsdorf R: Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation 2006;113:1203-1212.
Heineke J, Ruetten H, Willenbockel C, Gross SC, Naguib M, Schaefer A, Kempf T, Hilfiker-Kleiner D, Caroni P, Kraft T, Kaiser RA, Molkentin JD, Drexler H, Wollert KC: Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc. Proc Natl Acad Sci USA 2005;102:1655-1660.
Luers C, Fialka F, Elgner A, Zhu D, Kockskamper J, von Lewinski D, Pieske B: Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force response. Cardiovasc Res 2005;68:454-463.
Maier LS, Wahl-Schott C, Horn W, Weichert S, Pagel C, Wagner S, Dybkova N, Muller OJ, Nabauer M, Franz WM, Pieske B: Increased SR Ca(2+) cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats. Cardiovasc Res 2005;67:636-646.
von Lewinski D, Bruns S, Walther S, Kogler H, Pieske B: Insulin causes [Ca2+]i-dependent and [Ca2+]i-independent positive inotropic effects in failing human myocardium. Circulation 2005;111:2588-2595.
Kindermann M, Maack C, Schaller S, Finkler N, Schmidt KI, Laer S, Wuttke H, Schafers HJ, Bohm M: Carvedilol but not metoprolol reduces beta-adrenergic responsiveness after complete elimination from plasma in vivo. Circulation 2004;109:3182-3190.